Chrome offers built in support for a number of popular browsers other than Google, but there may be some that you'll be using frequently that Chrome doesn't offer. Start by going to the wrench icon, then options, and click on "manage" default search. If you see a search engine you want to make your default, select it and push the button that says "make default".
Adding a new search engine to the list is a bit more involved. Say you're going to use trickzys.blogspot.com regularly. You could always navigate to the page, but it's easier and more elegant to do this:
Go to trickzys.blogspot.com and do a search for anything. Then copy the url onto a text page and substitute "%s" for the search term. Now go back to the search options box, fill in the top two fields with the appropriate name and keyword and then cut and paste the text string you just saved into the third field. When you want to use trickzys, go to the browser's address bar, delete whatever text is in it, type trickzys(or whatever name you gave it) and press the "tab" key. You then type in the search terms, and Chrome forwards it to trickzys which then give you the results.
